GRK Labs team has extensive experience in sugar/base modifications, scaffold synthesis and phosphonates synthesis. We provide quality products with fast turnaround time and competitive price.

Capabilities

  • Modification of base
    • A, U, G, C modifications
    • Metal mediated modification (Suzuki, Stille, Heck, Negishi, Sonogashira and Buchwalrd Amination)
    • C2, C6, C8 of Base modification
    • Fluorination
  • Modification of Sugar
    • Deoxy spirocyclic Nucleosides
    • Fluorination
    • Methylation
    • Alkylation
  • Synthesis of Nucleoside scaffold/building blocks
  • Library synthesis of Nucleoside derivatives
  • Acyclic Nucleosides
  • Bicyclic and Tricyclic Nucleosides
  • Nucleoside Phosphate Esters
  • Scale-ups in multi-gram quantities